Clinical applications of melatonin in circadian disorders

Chronobiological disorders and syndromes include seasonal affective disorder (SAD), total blindness, advanced and delayed sleep phase syndrome, jet lag, and shift work maladaptation. These disorders are treated by adjusting circadian phase, using appropriately timed bright light exposure and melaton...

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Detalles Bibliográficos
Autor principal: Lewy, Alfred J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Les Laboratoires Servier 2003
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181782/
https://www.ncbi.nlm.nih.gov/pubmed/22033851
Descripción
Sumario:Chronobiological disorders and syndromes include seasonal affective disorder (SAD), total blindness, advanced and delayed sleep phase syndrome, jet lag, and shift work maladaptation. These disorders are treated by adjusting circadian phase, using appropriately timed bright light exposure and melatonin administration (at doses of 0.5 mg or less). In some cases, it may be necessary to measure internal circadían phase, using the time when endogenous melatonin levels rise.

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