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New insights into secondary prevention in post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) is unique amongst psychiatric disorders in two ways. Firstly, there is usually a very clear point of onset- the traumatic event The second unique feature of PTSD is that it is characterized by a failure of the normal response to resolve. Given these two characte...

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Autores principales: Zohar, Joseph, Juven-Wetzler, Alzbeta, Sonnino, Rachel, Cwikel-Hamzany, Shlomit, Balaban, Evgenya, Cohen, Hagit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Les Laboratoires Servier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182005/
https://www.ncbi.nlm.nih.gov/pubmed/22033784
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author Zohar, Joseph
Juven-Wetzler, Alzbeta
Sonnino, Rachel
Cwikel-Hamzany, Shlomit
Balaban, Evgenya
Cohen, Hagit
author_facet Zohar, Joseph
Juven-Wetzler, Alzbeta
Sonnino, Rachel
Cwikel-Hamzany, Shlomit
Balaban, Evgenya
Cohen, Hagit
author_sort Zohar, Joseph
collection PubMed
description Post-traumatic stress disorder (PTSD) is unique amongst psychiatric disorders in two ways. Firstly, there is usually a very clear point of onset- the traumatic event The second unique feature of PTSD is that it is characterized by a failure of the normal response to resolve. Given these two characteristics, PTSD appears a good candidate for secondary prevention, ie, interventions immediately after the trauma. Evidence available starting from current concepts and contemporary research of potential secondary prevention interventions are presented. Common practices in the aftermath of trauma such as debriefing and benzodiazepines need to be carefully considered, taking into account their potential harm to the spontaneous recovery process, and the trajectory of PTSD, and not only judging them according to their immediate (comforting) effects. A discussion of the balance required between aiding recovery but not interfering with the potent natural resolution of symptoms (that is expected in most cases), along with potential avenues of future research, are presented. Results of a small pilot study with a single intervention of hydrocortisone immediately after trauma appear to be promising, and clearly indicate the need for further studies.
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spelling pubmed-31820052011-10-27 New insights into secondary prevention in post-traumatic stress disorder Zohar, Joseph Juven-Wetzler, Alzbeta Sonnino, Rachel Cwikel-Hamzany, Shlomit Balaban, Evgenya Cohen, Hagit Dialogues Clin Neurosci Pharmacological Aspects Post-traumatic stress disorder (PTSD) is unique amongst psychiatric disorders in two ways. Firstly, there is usually a very clear point of onset- the traumatic event The second unique feature of PTSD is that it is characterized by a failure of the normal response to resolve. Given these two characteristics, PTSD appears a good candidate for secondary prevention, ie, interventions immediately after the trauma. Evidence available starting from current concepts and contemporary research of potential secondary prevention interventions are presented. Common practices in the aftermath of trauma such as debriefing and benzodiazepines need to be carefully considered, taking into account their potential harm to the spontaneous recovery process, and the trajectory of PTSD, and not only judging them according to their immediate (comforting) effects. A discussion of the balance required between aiding recovery but not interfering with the potent natural resolution of symptoms (that is expected in most cases), along with potential avenues of future research, are presented. Results of a small pilot study with a single intervention of hydrocortisone immediately after trauma appear to be promising, and clearly indicate the need for further studies. Les Laboratoires Servier 2011-09 /pmc/articles/PMC3182005/ /pubmed/22033784 Text en Copyright: © 2011 LLS http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Pharmacological Aspects
Zohar, Joseph
Juven-Wetzler, Alzbeta
Sonnino, Rachel
Cwikel-Hamzany, Shlomit
Balaban, Evgenya
Cohen, Hagit
New insights into secondary prevention in post-traumatic stress disorder
title New insights into secondary prevention in post-traumatic stress disorder
title_full New insights into secondary prevention in post-traumatic stress disorder
title_fullStr New insights into secondary prevention in post-traumatic stress disorder
title_full_unstemmed New insights into secondary prevention in post-traumatic stress disorder
title_short New insights into secondary prevention in post-traumatic stress disorder
title_sort new insights into secondary prevention in post-traumatic stress disorder
topic Pharmacological Aspects
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182005/
https://www.ncbi.nlm.nih.gov/pubmed/22033784
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