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Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think
Notch signaling is often considered a model hematopoietic proto-oncogene because of its role as the main trigger of T cell acute lymphoblastic leukemia (T-ALL). Although its role in T-ALL is well characterized and further supported by a high frequency of activating NOTCH1 mutations in T-ALL patients...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182047/ https://www.ncbi.nlm.nih.gov/pubmed/21948802 http://dx.doi.org/10.1084/jem.20111855 |