Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think

Notch signaling is often considered a model hematopoietic proto-oncogene because of its role as the main trigger of T cell acute lymphoblastic leukemia (T-ALL). Although its role in T-ALL is well characterized and further supported by a high frequency of activating NOTCH1 mutations in T-ALL patients...

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Detalles Bibliográficos
Autores principales: Lobry, Camille, Oh, Philmo, Aifantis, Iannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182047/
https://www.ncbi.nlm.nih.gov/pubmed/21948802
http://dx.doi.org/10.1084/jem.20111855

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