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Sustained suppression by Foxp3(+) regulatory T cells is vital for infectious transplantation tolerance

A paradigm shift in immunology has been the recent discovery of regulatory T cells (T reg cells), of which CD4(+)Foxp3(+) cells are proven as essential to self-tolerance. Using transgenic B6.Foxp3(hCD2) mice to isolate and ablate Foxp3(+) T reg cells with an anti-hCD2 antibody, we show for the first...

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Detalles Bibliográficos
Autores principales:	Kendal, Adrian R., Chen, Ye, Regateiro, Frederico S., Ma, Jianbo, Adams, Elizabeth, Cobbold, Stephen P., Hori, Shohei, Waldmann, Herman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182049/ https://www.ncbi.nlm.nih.gov/pubmed/21875958 http://dx.doi.org/10.1084/jem.20110767

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