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Response to dexamethasone is glucose-sensitive in multiple myeloma cell lines

BACKGROUND: Hyperglycemia is among the major side effects of dexamethasone (DEX). Glucose or glucocorticoid (GC) regulates the expression of thioredoxin-interacting protein (TXNIP) that controls the production of reactive oxygen species (ROS) through the modulation of thioredoxin (TRX) activity. MET...

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Detalles Bibliográficos
Autores principales:	Friday, Ellen, Ledet, Johnathan, Turturro, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182135/ https://www.ncbi.nlm.nih.gov/pubmed/21910912 http://dx.doi.org/10.1186/1756-9966-30-81

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