Impaired Striatal Akt Signaling Disrupts Dopamine Homeostasis and Increases Feeding

BACKGROUND: The prevalence of obesity has increased dramatically worldwide. The obesity epidemic begs for novel concepts and therapeutic targets that cohesively address “food-abuse” disorders. We demonstrate a molecular link between impairment of a central kinase (Akt) involved in insulin signaling...

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Detalles Bibliográficos
Autores principales: Speed, Nicole, Saunders, Christine, Davis, Adeola R., Owens, W. Anthony, Matthies, Heinrich J. G., Saadat, Sanaz, Kennedy, Jack P., Vaughan, Roxanne A., Neve, Rachael L., Lindsley, Craig W., Russo, Scott J., Daws, Lynette C., Niswender1, Kevin D., Galli, Aurelio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182178/
https://www.ncbi.nlm.nih.gov/pubmed/21969871
http://dx.doi.org/10.1371/journal.pone.0025169

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