Acetylation of the Proto-Oncogene EVI1 Abrogates Bcl-xL Promoter Binding and Induces Apoptosis

EVI1 (Ecotropic Viral Integration site I), which was originally identified as a myeloid transforming gene by means of retroviral insertional mutagenesis in mouse leukemia, encodes a nuclear DNA binding zinc finger protein. The presence of zinc fingers that are able to bind to specific sequences of D...

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Detalles Bibliográficos
Autores principales: Pradhan, Anjan Kumar, Mohapatra, Alok Das, Nayak, Kasturi Bala, Chakraborty, Soumen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182211/
https://www.ncbi.nlm.nih.gov/pubmed/21980434
http://dx.doi.org/10.1371/journal.pone.0025370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182211/
https://www.ncbi.nlm.nih.gov/pubmed/21980434
http://dx.doi.org/10.1371/journal.pone.0025370

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