A Systems Genetics Approach Provides a Bridge from Discovered Genetic Variants to Biological Pathways in Rheumatoid Arthritis

Genome-wide association studies (GWAS) have yielded novel genetic loci underlying common diseases. We propose a systems genetics approach to utilize these discoveries for better understanding of the genetic architecture of rheumatoid arthritis (RA). Current evidence of genetic associations with RA w...

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Detalles Bibliográficos
Autores principales: Nakaoka, Hirofumi, Cui, Tailin, Tajima, Atsushi, Oka, Akira, Mitsunaga, Shigeki, Kashiwase, Koichi, Homma, Yasuhiko, Sato, Shinji, Suzuki, Yasuo, Inoko, Hidetoshi, Inoue, Ituro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182219/
https://www.ncbi.nlm.nih.gov/pubmed/21980439
http://dx.doi.org/10.1371/journal.pone.0025389

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