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Long-Range Intra-Protein Communication Can Be Transmitted by Correlated Side-Chain Fluctuations Alone
Allosteric regulation is a key component of cellular communication, but the way in which information is passed from one site to another within a folded protein is not often clear. While backbone motions have long been considered essential for long-range information conveyance, side-chain motions hav...
Autores principales: | DuBay, Kateri H., Bothma, Jacques P., Geissler, Phillip L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182858/ https://www.ncbi.nlm.nih.gov/pubmed/21980271 http://dx.doi.org/10.1371/journal.pcbi.1002168 |
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