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DNA methylation of SPARC and chronic low back pain

BACKGROUND: The extracellular matrix protein SPARC (Secreted Protein, Acidic, Rich in Cysteine) has been linked to degeneration of the intervertebral discs and chronic low back pain (LBP). In humans, SPARC protein expression is decreased as a function of age and disc degeneration. In mice, inactivat...

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Detalles Bibliográficos
Autores principales:	Tajerian, Maral, Alvarado, Sebastian, Millecamps, Magali, Dashwood, Thomas, Anderson, Kathleen M, Haglund, Lisbet, Ouellet, Jean, Szyf, Moshe, Stone, Laura S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182907/ https://www.ncbi.nlm.nih.gov/pubmed/21867537 http://dx.doi.org/10.1186/1744-8069-7-65

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