Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α, releasing matrix metalloproteinase-9 and migrating in vitro

BACKGROUND: Increased matrix metalloproteinase (MMP)-9 in the plasma and brain is associated with blood-brain barrier (BBB) disruption through proteolytic activity in neuroinflammatory diseases. MMP-9 is present in the brain microvasculature and its vicinity, where brain microvascular endothelial ce...

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Detalles Bibliográficos
Autores principales: Takata, Fuyuko, Dohgu, Shinya, Matsumoto, Junichi, Takahashi, Hiroyuki, Machida, Takashi, Wakigawa, Tomoya, Harada, Eriko, Miyaji, Haruki, Koga, Mitsuhisa, Nishioku, Tsuyoshi, Yamauchi, Atsushi, Kataoka, Yasufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182916/
https://www.ncbi.nlm.nih.gov/pubmed/21867555
http://dx.doi.org/10.1186/1742-2094-8-106

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