Recurrent Signature Patterns in HIV-1 B Clade Envelope Glycoproteins Associated with either Early or Chronic Infections

Here we have identified HIV-1 B clade Envelope (Env) amino acid signatures from early in infection that may be favored at transmission, as well as patterns of recurrent mutation in chronic infection that may reflect common pathways of immune evasion. To accomplish this, we compared thousands of sequ...

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Detalles Bibliográficos
Autores principales: Gnanakaran, S., Bhattacharya, Tanmoy, Daniels, Marcus, Keele, Brandon F., Hraber, Peter T., Lapedes, Alan S., Shen, Tongye, Gaschen, Brian, Krishnamoorthy, Mohan, Li, Hui, Decker, Julie M., Salazar-Gonzalez, Jesus F., Wang, Shuyi, Jiang, Chunlai, Gao, Feng, Swanstrom, Ronald, Anderson, Jeffrey A., Ping, Li-Hua, Cohen, Myron S., Markowitz, Martin, Goepfert, Paul A., Saag, Michael S., Eron, Joseph J., Hicks, Charles B., Blattner, William A., Tomaras, Georgia D., Asmal, Mohammed, Letvin, Norman L., Gilbert, Peter B., DeCamp, Allan C., Magaret, Craig A., Schief, William R., Ban, Yih-En Andrew, Zhang, Ming, Soderberg, Kelly A., Sodroski, Joseph G., Haynes, Barton F., Shaw, George M., Hahn, Beatrice H., Korber, Bette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182927/
https://www.ncbi.nlm.nih.gov/pubmed/21980282
http://dx.doi.org/10.1371/journal.ppat.1002209

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