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Mobile DNA transposition in somatic cells
It had been long assumed that almost all insertions of mobile DNA elements occurred during germ-cell development rather than in somatic-cell development, but solid evidence for transposition in somatic cells is now accumulating. To add to this evidence, a recent paper in Mobile DNA reports the somat...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182954/ https://www.ncbi.nlm.nih.gov/pubmed/21958341 http://dx.doi.org/10.1186/1741-7007-9-62 |
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| author | Kazazian, Haig H |
| author_facet | Kazazian, Haig H |
| author_sort | Kazazian, Haig H |
| collection | PubMed |
| description | It had been long assumed that almost all insertions of mobile DNA elements occurred during germ-cell development rather than in somatic-cell development, but solid evidence for transposition in somatic cells is now accumulating. To add to this evidence, a recent paper in Mobile DNA reports the somatic transposition of a site-specific retrotransposon, R2, into its insertion site in 28S ribosomal DNA in Drosophila embryos. See research article: http://www.mobilednajournal.com/content/2/1/11 |
| format | Online Article Text |
| id | pubmed-3182954 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2011 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-31829542011-09-30 Mobile DNA transposition in somatic cells Kazazian, Haig H BMC Biol Commentary It had been long assumed that almost all insertions of mobile DNA elements occurred during germ-cell development rather than in somatic-cell development, but solid evidence for transposition in somatic cells is now accumulating. To add to this evidence, a recent paper in Mobile DNA reports the somatic transposition of a site-specific retrotransposon, R2, into its insertion site in 28S ribosomal DNA in Drosophila embryos. See research article: http://www.mobilednajournal.com/content/2/1/11 BioMed Central 2011-09-29 /pmc/articles/PMC3182954/ /pubmed/21958341 http://dx.doi.org/10.1186/1741-7007-9-62 Text en Copyright ©2011 Kazazian; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Commentary Kazazian, Haig H Mobile DNA transposition in somatic cells |
| title | Mobile DNA transposition in somatic cells |
| title_full | Mobile DNA transposition in somatic cells |
| title_fullStr | Mobile DNA transposition in somatic cells |
| title_full_unstemmed | Mobile DNA transposition in somatic cells |
| title_short | Mobile DNA transposition in somatic cells |
| title_sort | mobile dna transposition in somatic cells |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182954/ https://www.ncbi.nlm.nih.gov/pubmed/21958341 http://dx.doi.org/10.1186/1741-7007-9-62 |
| work_keys_str_mv | AT kazazianhaigh mobilednatranspositioninsomaticcells |