HIV infection of thymocytes inhibits IL-7 activity without altering CD127 expression

BACKGROUND: Thymic function is altered in HIV infection and characterized by dysregulation of the thymic epithelial network, reduced thymic output and ultimately an impaired naïve T-cell pool. The IL-7/IL-7 receptor (IL-7R) signalling pathway is critical for the maturation and differentiation of thy...

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Detalles Bibliográficos
Autores principales: Young, Charlene D, Angel, Jonathan B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182983/
https://www.ncbi.nlm.nih.gov/pubmed/21920046
http://dx.doi.org/10.1186/1742-4690-8-72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182983/
https://www.ncbi.nlm.nih.gov/pubmed/21920046
http://dx.doi.org/10.1186/1742-4690-8-72

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