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HIV infection of thymocytes inhibits IL-7 activity without altering CD127 expression
BACKGROUND: Thymic function is altered in HIV infection and characterized by dysregulation of the thymic epithelial network, reduced thymic output and ultimately an impaired naïve T-cell pool. The IL-7/IL-7 receptor (IL-7R) signalling pathway is critical for the maturation and differentiation of thy...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182983/ https://www.ncbi.nlm.nih.gov/pubmed/21920046 http://dx.doi.org/10.1186/1742-4690-8-72 |