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High-Throughput Screen for Identifying Small Molecules That Target Fungal Zinc Homeostasis

Resistance to traditional antifungal drugs has increased significantly over the past three decades, making identification of novel antifungal agents and new targets an emerging priority. Based on the extraordinary zinc requirement of several fungal pathogens and their well-established sensitivity to...

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Detalles Bibliográficos
Autores principales: Simm, Claudia, Luan, Chi-Hao, Weiss, Eric, O'Halloran, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182986/
https://www.ncbi.nlm.nih.gov/pubmed/21980385
http://dx.doi.org/10.1371/journal.pone.0025136