Cargando…
High-Throughput Screen for Identifying Small Molecules That Target Fungal Zinc Homeostasis
Resistance to traditional antifungal drugs has increased significantly over the past three decades, making identification of novel antifungal agents and new targets an emerging priority. Based on the extraordinary zinc requirement of several fungal pathogens and their well-established sensitivity to...
Autores principales: | Simm, Claudia, Luan, Chi-Hao, Weiss, Eric, O'Halloran, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182986/ https://www.ncbi.nlm.nih.gov/pubmed/21980385 http://dx.doi.org/10.1371/journal.pone.0025136 |
Ejemplares similares
-
Zinc and Iron Homeostasis: Target-Based Drug Screening as New Route for Antifungal Drug Development
por: Simm, Claudia, et al.
Publicado: (2019) -
High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides
por: Yang, B., et al.
Publicado: (2015) -
Identifying small molecule probes of ENTPD5 through high throughput screening
por: Durst, Matthew A., et al.
Publicado: (2019) -
High-Throughput Small Molecule Screen Identifies Modulators of Mitochondrial Function in Neurons
por: Varkuti, Boglarka H., et al.
Publicado: (2020) -
High-Throughput Small Molecule Screen Identifies Modulators of Mitochondrial Function in Neurons
por: Varkuti, Boglarka H., et al.
Publicado: (2020)