A phosphatase threshold sets the level of Cdk1 activity in early mitosis in budding yeast

Entry into mitosis is initiated by synthesis of cyclins, which bind and activate cyclin-dependent kinase 1 (Cdk1). Cyclin synthesis is gradual, yet activation of Cdk1 occurs in a stepwise manner: a low level of Cdk1 activity is initially generated that triggers early mitotic events, which is followe...

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Detalles Bibliográficos
Autores principales: Harvey, Stacy L., Enciso, Germán, Dephoure, Noah, Gygi, Steven P., Gunawardena, Jeremy, Kellogg, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183015/
https://www.ncbi.nlm.nih.gov/pubmed/21849476
http://dx.doi.org/10.1091/mbc.E11-04-0340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183015/
https://www.ncbi.nlm.nih.gov/pubmed/21849476
http://dx.doi.org/10.1091/mbc.E11-04-0340

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