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Dysregulation of Gene Expression in the Artificial Human Trisomy Cells of Chromosome 8 Associated with Transformed Cell Phenotypes

A change in chromosome number, known as aneuploidy, is a common characteristic of cancer. Aneuploidy disrupts gene expression in human cancer cells and immortalized human epithelial cells, but not in normal human cells. However, the relationship between aneuploidy and cancer remains unclear. To stud...

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Detalles Bibliográficos
Autores principales: Nawata, Hisakatsu, Kashino, Genro, Tano, Keizo, Daino, Kazuhiro, Shimada, Yoshiya, Kugoh, Hiroyuki, Oshimura, Mitsuo, Watanabe, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183047/
https://www.ncbi.nlm.nih.gov/pubmed/21980425
http://dx.doi.org/10.1371/journal.pone.0025319