Aggravation of Chronic Stress Effects on Hippocampal Neurogenesis and Spatial Memory in LPA(1) Receptor Knockout Mice

BACKGROUND: The lysophosphatidic acid LPA(1) receptor regulates plasticity and neurogenesis in the adult hippocampus. Here, we studied whether absence of the LPA(1) receptor modulated the detrimental effects of chronic stress on hippocampal neurogenesis and spatial memory. METHODOLOGY/PRINCIPAL FIND...

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Detalles Bibliográficos
Autores principales: Castilla-Ortega, Estela, Hoyo-Becerra, Carolina, Pedraza, Carmen, Chun, Jerold, Rodríguez De Fonseca, Fernando, Estivill-Torrús, Guillermo, Santín, Luis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183048/
https://www.ncbi.nlm.nih.gov/pubmed/21980482
http://dx.doi.org/10.1371/journal.pone.0025522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183048/
https://www.ncbi.nlm.nih.gov/pubmed/21980482
http://dx.doi.org/10.1371/journal.pone.0025522

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