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Oral-Nasopharyngeal Dendritic Cells Mediate T Cell-Independent IgA Class Switching on B-1 B Cells

Native cholera toxin (nCT) as a nasal adjuvant was shown to elicit increased levels of T-independent S-IgA antibody (Ab) responses through IL-5- IL-5 receptor interactions between CD4(+) T cells and IgA(+) B-1 B cells in murine submandibular glands (SMGs) and nasal passages (NPs). Here, we further i...

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Detalles Bibliográficos
Autores principales: Kataoka, Kosuke, Fujihashi, Keiko, Terao, Yutaka, Gilbert, Rebekah S., Sekine, Shinichi, Kobayashi, Ryoki, Fukuyama, Yoshiko, Kawabata, Shigetada, Fujihashi, Kohtaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183055/
https://www.ncbi.nlm.nih.gov/pubmed/21980444
http://dx.doi.org/10.1371/journal.pone.0025396