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ProteinSeq: High-Performance Proteomic Analyses by Proximity Ligation and Next Generation Sequencing
Despite intense interest, methods that provide enhanced sensitivity and specificity in parallel measurements of candidate protein biomarkers in numerous samples have been lacking. We present herein a multiplex proximity ligation assay with readout via realtime PCR or DNA sequencing (ProteinSeq). We...
Autores principales: | Darmanis, Spyros, Nong, Rachel Yuan, Vänelid, Johan, Siegbahn, Agneta, Ericsson, Olle, Fredriksson, Simon, Bäcklin, Christofer, Gut, Marta, Heath, Simon, Gut, Ivo Glynne, Wallentin, Lars, Gustafsson, Mats G., Kamali-Moghaddam, Masood, Landegren, Ulf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183061/ https://www.ncbi.nlm.nih.gov/pubmed/21980495 http://dx.doi.org/10.1371/journal.pone.0025583 |
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