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Epigenetic repression of E-cadherin expression by Hepatitis B virus x Antigen (HBx) in liver cancer

Loss of E-cadherin is associated with acquisition of metastatic capacity. Numerous studies suggest histone deacetylation and/or hypermethylation of CpG islands in E-cadherin gene (CDH1) are major mechanisms responsible for E-cadherin silencing in different tumors and cancer cell lines. The Hepatitis...

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Detalles Bibliográficos
Autores principales:	Arzumanyan, Alla, Friedman, Tiffany, Kotei, Enoch, Ng, Irene O.L., Lian, Zhaorui, Feitelson, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183380/ https://www.ncbi.nlm.nih.gov/pubmed/21706058 http://dx.doi.org/10.1038/onc.2011.255

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