HIV-1 protease inhibitor mutations affect the development of HIV-1 resistance to the maturation inhibitor bevirimat

BACKGROUND: Maturation inhibitors are an experimental class of antiretrovirals that inhibit Human Immunodeficiency Virus (HIV) particle maturation, the structural rearrangement required to form infectious virus particles. This rearrangement is triggered by the ordered cleavage of the precursor Gag p...

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Detalles Bibliográficos
Autores principales: Fun, Axel, van Maarseveen, Noortje M, Pokorná, Jana, Maas, Renée EM, Schipper, Pauline J, Konvalinka, Jan, Nijhuis, Monique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184055/
https://www.ncbi.nlm.nih.gov/pubmed/21864346
http://dx.doi.org/10.1186/1742-4690-8-70

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184055/
https://www.ncbi.nlm.nih.gov/pubmed/21864346
http://dx.doi.org/10.1186/1742-4690-8-70

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