Practical Tools to Implement Massive Parallel Pyrosequencing of PCR Products in Next Generation Molecular Diagnostics

Despite improvements in terms of sequence quality and price per basepair, Sanger sequencing remains restricted to screening of individual disease genes. The development of massively parallel sequencing (MPS) technologies heralded an era in which molecular diagnostics for multigenic disorders becomes...

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Detalles Bibliográficos
Autores principales: De Leeneer, Kim, De Schrijver, Joachim, Clement, Lieven, Baetens, Machteld, Lefever, Steve, De Keulenaer, Sarah, Van Criekinge, Wim, Deforce, Dieter, Van Nieuwerburgh, Filip, Bekaert, Sofie, Pattyn, Filip, De Wilde, Bram, Coucke, Paul, Vandesompele, Jo, Claes, Kathleen, Hellemans, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184136/
https://www.ncbi.nlm.nih.gov/pubmed/21980484
http://dx.doi.org/10.1371/journal.pone.0025531

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