Phase I Randomised Clinical Trial of an HIV-1(CN54), Clade C, Trimeric Envelope Vaccine Candidate Delivered Vaginally

We conducted a phase 1 double-blind randomised controlled trial (RCT) of a HIV-1 envelope protein (CN54 gp140) candidate vaccine delivered vaginally to assess immunogenicity and safety. It was hypothesised that repeated delivery of gp140 may facilitate antigen uptake and presentation at this mucosal...

Descripción completa

Detalles Bibliográficos
Autores principales: Lewis, David J., Fraser, Carol A., Mahmoud, Abdel N., Wiggins, Rebecca C., Woodrow, Maria, Cope, Alethea, Cai, Chun, Giemza, Rafaela, Jeffs, Simon A., Manoussaka, Maria, Cole, Tom, Cranage, Martin P., Shattock, Robin J., Lacey, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184147/
https://www.ncbi.nlm.nih.gov/pubmed/21984924
http://dx.doi.org/10.1371/journal.pone.0025165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184147/
https://www.ncbi.nlm.nih.gov/pubmed/21984924
http://dx.doi.org/10.1371/journal.pone.0025165

Ejemplares similares