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Induction of Eosinophil Apoptosis by the Cyclin-Dependent Kinase Inhibitor AT7519 Promotes the Resolution of Eosinophil-Dominant Allergic Inflammation
BACKGROUND: Eosinophils not only defend the body against parasitic infection but are also involved in pathological inflammatory allergic diseases such as asthma, allergic rhinitis and contact dermatitis. Clearance of apoptotic eosinophils by macrophages is a key process responsible for driving the r...
Autores principales: | Alessandri, Ana L., Duffin, Rodger, Leitch, Andrew E., Lucas, Christopher D., Sheldrake, Tara A., Dorward, David A., Hirani, Nik, Pinho, Vanessa, de Sousa, Lirlândia Pires, Teixeira, Mauro M., Lyons, John F., Haslett, Christopher, Rossi, Adriano G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184151/ https://www.ncbi.nlm.nih.gov/pubmed/21984938 http://dx.doi.org/10.1371/journal.pone.0025683 |
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