Pharmacological Blockade of TRPM8 Ion Channels Alters Cold and Cold Pain Responses in Mice

TRPM8 (Transient Receptor Potential Melastatin-8) is a cold- and menthol-gated ion channel necessary for the detection of cold temperatures in the mammalian peripheral nervous system. Functioning TRPM8 channels are required for behavioral responses to innocuous cool, noxious cold, injury-evoked cold...

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Detalles Bibliográficos
Autores principales: Knowlton, Wendy M., Daniels, Richard L., Palkar, Radhika, McCoy, Daniel D., McKemy, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184174/
https://www.ncbi.nlm.nih.gov/pubmed/21984952
http://dx.doi.org/10.1371/journal.pone.0025894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184174/
https://www.ncbi.nlm.nih.gov/pubmed/21984952
http://dx.doi.org/10.1371/journal.pone.0025894

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