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Pharmacological Blockade of TRPM8 Ion Channels Alters Cold and Cold Pain Responses in Mice
TRPM8 (Transient Receptor Potential Melastatin-8) is a cold- and menthol-gated ion channel necessary for the detection of cold temperatures in the mammalian peripheral nervous system. Functioning TRPM8 channels are required for behavioral responses to innocuous cool, noxious cold, injury-evoked cold...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184174/ https://www.ncbi.nlm.nih.gov/pubmed/21984952 http://dx.doi.org/10.1371/journal.pone.0025894 |