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Crystal Structure of the β(2)Adrenergic Receptor-Gs protein complex
G protein-coupled receptors (GPCRs) are responsible for the majority of cellular responses to hormones and neurotransmitters as well as the senses of sight, olfaction and taste. The paradigm of GPCR signaling is the activation of a heterotrimeric GTP binding protein (G protein) by an agonist-occupie...
Autores principales: | Rasmussen, Søren G.F., DeVree, Brian T., Zou, Yaozhong, Kruse, Andrew C., Chung, Ka Young, Kobilka, Tong Sun, Thian, Foon Sun, Chae, Pil Seok, Pardon, Els, Calinski, Diane, Mathiesen, Jesper M., Shah, Syed T. A., Lyons, Joseph A., Caffrey, Martin, Gellman, Samuel H., Steyaert, Jan, Skiniotis, Georgios, Weis, William I., Sunahara, Roger K., Kobilka, Brian K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184188/ https://www.ncbi.nlm.nih.gov/pubmed/21772288 http://dx.doi.org/10.1038/nature10361 |
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