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Innate immune recognition of bacterial ligands by NAIPs dictates inflammasome specificity
Inflammasomes are a family of cytosolic multiprotein complexes that initiate innate immune responses to pathogenic microbes by activating the CASPASE1 (CASP1) protease(1,2). Although genetic data support a critical role for inflammasomes in immune defense and inflammatory diseases(3), the molecular...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184209/ https://www.ncbi.nlm.nih.gov/pubmed/21874021 http://dx.doi.org/10.1038/nature10394 |