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Non-compaction of the ventricular myocardium

Non-compaction of the left ventricle (LVNC) is a disorder of endomyocardial morphogenesis that results in multiple trabeculations in the left ventricular (LV) myocardium. This rare disorder is characterized by an excessively prominent trabecular meshwork and deep intratrabecular recesses. This idiop...

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Autores principales: VIZZARDI, ENRICO, NODARI, SAVINA, METRA, MARCO, DEI CAS, LIVIO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184674/
https://www.ncbi.nlm.nih.gov/pubmed/21977268
http://dx.doi.org/10.4081/hi.2006.178
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author VIZZARDI, ENRICO
NODARI, SAVINA
METRA, MARCO
DEI CAS, LIVIO
author_facet VIZZARDI, ENRICO
NODARI, SAVINA
METRA, MARCO
DEI CAS, LIVIO
author_sort VIZZARDI, ENRICO
collection PubMed
description Non-compaction of the left ventricle (LVNC) is a disorder of endomyocardial morphogenesis that results in multiple trabeculations in the left ventricular (LV) myocardium. This rare disorder is characterized by an excessively prominent trabecular meshwork and deep intratrabecular recesses. This idiopathic cardiomyopathy is characterized by an altered structure of the myocardial wall as a result of intrauterine arrest of compaction of the myocardial fibers in the absence of any coexisting congenital lesion. It can be associated with neuromuscular disorders and can co-exist with other cardiac malformations, and it is accompanied by depressed ventricular function, systemic embolism and ventricular arrhythmia. Echocardiography is the method of choice for diagnosing LVNC, but the correct diagnosis is often missed or delayed due to a lack of knowledge concerning this uncommon disease and its similarity to other diseases of the myocardium and endocardium. There is a two-layered structure of the myocardial wall consisting of a thin compacted epicardial layer and a thick non-compacted endocardial layer with prominent trabeculations and deep recesses.
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spelling pubmed-31846742011-10-05 Non-compaction of the ventricular myocardium VIZZARDI, ENRICO NODARI, SAVINA METRA, MARCO DEI CAS, LIVIO Heart Int Article Non-compaction of the left ventricle (LVNC) is a disorder of endomyocardial morphogenesis that results in multiple trabeculations in the left ventricular (LV) myocardium. This rare disorder is characterized by an excessively prominent trabecular meshwork and deep intratrabecular recesses. This idiopathic cardiomyopathy is characterized by an altered structure of the myocardial wall as a result of intrauterine arrest of compaction of the myocardial fibers in the absence of any coexisting congenital lesion. It can be associated with neuromuscular disorders and can co-exist with other cardiac malformations, and it is accompanied by depressed ventricular function, systemic embolism and ventricular arrhythmia. Echocardiography is the method of choice for diagnosing LVNC, but the correct diagnosis is often missed or delayed due to a lack of knowledge concerning this uncommon disease and its similarity to other diseases of the myocardium and endocardium. There is a two-layered structure of the myocardial wall consisting of a thin compacted epicardial layer and a thick non-compacted endocardial layer with prominent trabeculations and deep recesses. PAGEPress Publications 2006-12-15 /pmc/articles/PMC3184674/ /pubmed/21977268 http://dx.doi.org/10.4081/hi.2006.178 Text en © Wichtig Editore, 2007
spellingShingle Article
VIZZARDI, ENRICO
NODARI, SAVINA
METRA, MARCO
DEI CAS, LIVIO
Non-compaction of the ventricular myocardium
title Non-compaction of the ventricular myocardium
title_full Non-compaction of the ventricular myocardium
title_fullStr Non-compaction of the ventricular myocardium
title_full_unstemmed Non-compaction of the ventricular myocardium
title_short Non-compaction of the ventricular myocardium
title_sort non-compaction of the ventricular myocardium
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184674/
https://www.ncbi.nlm.nih.gov/pubmed/21977268
http://dx.doi.org/10.4081/hi.2006.178
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