Imaging with second-harmonic radiation probes in living tissue

We demonstrate that second-harmonic radiation imaging probes are efficient biomarkers for imaging in living tissue. We show that 100 nm and 300 nm BaTiO(3) nanoparticles used as contrast markers could be detected through 50 μm and 120 μm of mouse tail tissue in vitro or in vivo. Experimental results...

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Detalles Bibliográficos
Autores principales: Grange, Rachel, Lanvin, Thomas, Hsieh, Chia-Lung, Pu, Ye, Psaltis, Demetri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2011
Materias:
Molecular Imaging and Probe Development
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184862/
https://www.ncbi.nlm.nih.gov/pubmed/21991545
http://dx.doi.org/10.1364/BOE.2.002532
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author Grange, Rachel
Lanvin, Thomas
Hsieh, Chia-Lung
Pu, Ye
Psaltis, Demetri
author_facet Grange, Rachel
Lanvin, Thomas
Hsieh, Chia-Lung
Pu, Ye
Psaltis, Demetri
author_sort Grange, Rachel
collection PubMed
description We demonstrate that second-harmonic radiation imaging probes are efficient biomarkers for imaging in living tissue. We show that 100 nm and 300 nm BaTiO(3) nanoparticles used as contrast markers could be detected through 50 μm and 120 μm of mouse tail tissue in vitro or in vivo. Experimental results and Monte-Carlo simulations are in good agreement.
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spelling pubmed-31848622011-10-11 Imaging with second-harmonic radiation probes in living tissue Grange, Rachel Lanvin, Thomas Hsieh, Chia-Lung Pu, Ye Psaltis, Demetri Biomed Opt Express Molecular Imaging and Probe Development We demonstrate that second-harmonic radiation imaging probes are efficient biomarkers for imaging in living tissue. We show that 100 nm and 300 nm BaTiO(3) nanoparticles used as contrast markers could be detected through 50 μm and 120 μm of mouse tail tissue in vitro or in vivo. Experimental results and Monte-Carlo simulations are in good agreement. Optical Society of America 2011-08-02 /pmc/articles/PMC3184862/ /pubmed/21991545 http://dx.doi.org/10.1364/BOE.2.002532 Text en ©2011 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Molecular Imaging and Probe Development
Grange, Rachel
Lanvin, Thomas
Hsieh, Chia-Lung
Pu, Ye
Psaltis, Demetri
Imaging with second-harmonic radiation probes in living tissue
title Imaging with second-harmonic radiation probes in living tissue
title_full Imaging with second-harmonic radiation probes in living tissue
title_fullStr Imaging with second-harmonic radiation probes in living tissue
title_full_unstemmed Imaging with second-harmonic radiation probes in living tissue
title_short Imaging with second-harmonic radiation probes in living tissue
title_sort imaging with second-harmonic radiation probes in living tissue
topic Molecular Imaging and Probe Development
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184862/
https://www.ncbi.nlm.nih.gov/pubmed/21991545
http://dx.doi.org/10.1364/BOE.2.002532
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AT psaltisdemetri imagingwithsecondharmonicradiationprobesinlivingtissue

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