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RAM, an RGDS Analog, Exerts Potent Anti-Melanoma Effects In Vitro and In Vivo

Peptides containing the RGD sequence are under continuous investigation given their ability to control cell adhesion and apoptosis. Since small peptides are quickly metabolized and degraded in vivo, developing analogs resistant to serum-induced degradation is a challenging task. RGD analogs develope...

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Detalles Bibliográficos
Autores principales: Aguzzi, Maria Simona, D'Arcangelo, Daniela, Giampietri, Claudia, Capogrossi, Maurizio C., Facchiano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184964/
https://www.ncbi.nlm.nih.gov/pubmed/21984914
http://dx.doi.org/10.1371/journal.pone.0025352