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RAM, an RGDS Analog, Exerts Potent Anti-Melanoma Effects In Vitro and In Vivo
Peptides containing the RGD sequence are under continuous investigation given their ability to control cell adhesion and apoptosis. Since small peptides are quickly metabolized and degraded in vivo, developing analogs resistant to serum-induced degradation is a challenging task. RGD analogs develope...
Autores principales: | Aguzzi, Maria Simona, D'Arcangelo, Daniela, Giampietri, Claudia, Capogrossi, Maurizio C., Facchiano, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184964/ https://www.ncbi.nlm.nih.gov/pubmed/21984914 http://dx.doi.org/10.1371/journal.pone.0025352 |
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