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Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD(+) oscillation

The Intracellular levels of nicotinamide adenine dinucleotide (NAD(+)) are rhythmic and controlled by the circadian clock. However, whether NAD(+) oscillation in turn contributes to circadian physiology is not fully understood. To address this question we analyzed mice mutated for the NAD(+) hydrola...

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Detalles Bibliográficos
Autores principales: Sahar, Saurabh, Nin, Veronica, Barbosa, Maria Thereza, Chini, Eduardo Nunes, Sassone-Corsi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184980/
https://www.ncbi.nlm.nih.gov/pubmed/21937766