α,β-D-Constrained Nucleic Acids Are Strong Terminators of Thermostable DNA Polymerases in Polymerase Chain Reaction

(S (C5′), R(P)) α,β-D- Constrained Nucleic Acids (CNA) are dinucleotide building blocks that can feature either B-type torsional angle values or non-canonical values, depending on their 5′C and P absolute stereochemistry. These CNA are modified neither on the nucleobase nor on the sugar structure an...

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Detalles Bibliográficos
Autores principales: Martínez, Olivier, Ecochard, Vincent, Mahéo, Sabrina, Gross, Grégori, Bodin, Pierre, Teissié, Justin, Escudier, Jean-Marc, Paquereau, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185000/
https://www.ncbi.nlm.nih.gov/pubmed/21991314
http://dx.doi.org/10.1371/journal.pone.0025510

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