Reduced mRNA and Protein Expression of the Genomic Caretaker RAD9A in Primary Fibroblasts of Individuals with Childhood and Independent Second Cancer

BACKGROUND: The etiology of secondary cancer in childhood cancer survivors is largely unclear. Exposure of normal somatic cells to radiation and/or chemotherapy can damage DNA and if not all DNA lesions are properly fixed, the mis-repair may lead to pathological consequences. It is plausible to assu...

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Detalles Bibliográficos
Autores principales: Weis, Eva, Schoen, Holger, Victor, Anja, Spix, Claudia, Ludwig, Marco, Schneider-Raetzke, Brigitte, Kohlschmidt, Nicolai, Bartsch, Oliver, Gerhold-Ay, Aslihan, Boehm, Nils, Grus, Franz, Haaf, Thomas, Galetzka, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185005/
https://www.ncbi.nlm.nih.gov/pubmed/21991345
http://dx.doi.org/10.1371/journal.pone.0025750

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