T-helper Cell-Mediated Proliferation and Cytokine Responses against Recombinant Merkel Cell Polyomavirus-Like Particles

The newly discovered Merkel Cell Polyomavirus (MCPyV) resides in approximately 80% of Merkel cell carcinomas (MCC). Causal role of MCPyV for this rare and aggressive skin cancer is suggested by monoclonal integration and truncation of large T (LT) viral antigen in MCC cells. The mutated MCPyV has re...

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Detalles Bibliográficos
Autores principales: Kumar, Arun, Chen, Tingting, Pakkanen, Sari, Kantele, Anu, Söderlund-Venermo, Maria, Hedman, Klaus, Franssila, Rauli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185038/
https://www.ncbi.nlm.nih.gov/pubmed/21991346
http://dx.doi.org/10.1371/journal.pone.0025751

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