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A SILAC-Based Screen for Methyl-CpG Binding Proteins Identifies RBP-J as a DNA Methylation and Sequence-Specific Binding Protein
BACKGROUND: DNA methylation is an epigenetic modification that plays a crucial role in a variety of biological processes. Methylated DNA is specifically bound by Methyl-CpG Binding Proteins (MBPs). Three different types of MBPs have been identified so far: the Methyl-CpG Binding Domain (MBD) family...
Autores principales: | Bartels, Stefanie J. J., Spruijt, Cornelia G., Brinkman, Arie B., Jansen, Pascal W. T. C., Vermeulen, Michiel, Stunnenberg, Hendrik G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185043/ https://www.ncbi.nlm.nih.gov/pubmed/21991380 http://dx.doi.org/10.1371/journal.pone.0025884 |
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