Cargando…
Genetic Ablation of CD68 Results in Mice with Increased Bone and Dysfunctional Osteoclasts
CD68 is a member of the lysosome associated membrane protein (LAMP) family that is restricted in its expression to cells of the monocyte/macrophage lineage. This lineage restriction includes osteoclasts, and, while previous studies of CD68 in macrophages and dendritic cells have proposed roles in li...
Autores principales: | Ashley, Jason W., Shi, Zhenqi, Zhao, Haibo, Li, Xingsheng, Kesterson, Robert A., Feng, Xu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185056/ https://www.ncbi.nlm.nih.gov/pubmed/21991369 http://dx.doi.org/10.1371/journal.pone.0025838 |
Ejemplares similares
-
Ablation of Tak1 in osteoclast progenitor leads to defects in skeletal growth and bone remodeling in mice
por: Qi, Bing, et al.
Publicado: (2014) -
Bone Microenvironment‐Suppressed T Cells Increase Osteoclast Formation and Osteolytic Bone Metastases in Mice
por: Arellano, Danna L., et al.
Publicado: (2022) -
Ablation of Y(1) receptor impairs osteoclast bone-resorbing activity
por: Sousa, Daniela M., et al.
Publicado: (2016) -
Mitochondrial dysfunction impairs osteogenesis, increases osteoclast activity, and accelerates age related bone loss
por: Dobson, Philip F., et al.
Publicado: (2020) -
Ablation of the Sam68 RNA Binding Protein Protects Mice from Age-Related Bone Loss
por: Richard, Stéphane, et al.
Publicado: (2005)