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No Immune Responses by the Expression of the Yeast Ndi1 Protein in Rats

BACKGROUND: The rotenone-insensitive internal NADH-quinone oxidoreductase from yeast, Ndi1, has been shown to work as a replacement molecule for complex I in the respiratory chain of mammalian mitochondria. In the so-called transkingdom gene therapy, one major concern is the fact that the yeast prot...

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Detalles Bibliográficos
Autores principales: Marella, Mathieu, Seo, Byoung Boo, Flotte, Terence R., Matsuno-Yagi, Akemi, Yagi, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185062/
https://www.ncbi.nlm.nih.gov/pubmed/21991386
http://dx.doi.org/10.1371/journal.pone.0025910