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No Immune Responses by the Expression of the Yeast Ndi1 Protein in Rats
BACKGROUND: The rotenone-insensitive internal NADH-quinone oxidoreductase from yeast, Ndi1, has been shown to work as a replacement molecule for complex I in the respiratory chain of mammalian mitochondria. In the so-called transkingdom gene therapy, one major concern is the fact that the yeast prot...
Autores principales: | Marella, Mathieu, Seo, Byoung Boo, Flotte, Terence R., Matsuno-Yagi, Akemi, Yagi, Takao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185062/ https://www.ncbi.nlm.nih.gov/pubmed/21991386 http://dx.doi.org/10.1371/journal.pone.0025910 |
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