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Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma
Glioblastoma (GBM) is a highly aggressive brain tumour, where patients respond poorly to radiotherapy and exhibit dismal survival outcomes. The mechanisms of radioresistance are not completely understood. However, cancer cells with an immature stem-like phenotype are hypothesised to play a role in r...
Autores principales: | Svendsen, Agnete, Verhoeff, Joost J. C., Immervoll, Heike, Brøgger, Jan C., Kmiecik, Justyna, Poli, Aurelie, Netland, Inger A., Prestegarden, Lars, Planagumà, Jesús, Torsvik, Anja, Kjersem, Anneli Bohne, Sakariassen, Per Ø., Heggdal, Jan I., Van Furth, Wouter R., Bjerkvig, Rolf, Lund-Johansen, Morten, Enger, Per Ø., Felsberg, Joerg, Brons, Nicolaas H. C., Tronstad, Karl J., Waha, Andreas, Chekenya, Martha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185228/ https://www.ncbi.nlm.nih.gov/pubmed/21863242 http://dx.doi.org/10.1007/s00401-011-0867-2 |
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