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Computational Modeling of Interacting VEGF and Soluble VEGF Receptor Concentration Gradients

Experimental data indicates that soluble vascular endothelial growth factor (VEGF) receptor 1 (sFlt-1) modulates the guidance cues provided to sprouting blood vessels by VEGF-A. To better delineate the role of sFlt-1 in VEGF signaling, we have developed an experimentally based computational model. T...

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Detalles Bibliográficos
Autores principales:	Hashambhoy, Yasmin L., Chappell, John C., Peirce, Shayn M., Bautch, Victoria L., Mac Gabhann, Feilim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185289/ https://www.ncbi.nlm.nih.gov/pubmed/22007175 http://dx.doi.org/10.3389/fphys.2011.00062

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