Molecular design of a splicing switch responsive to the RNA binding protein Tra2β

Tra2β regulates a number of splicing switches including activation of the human testis-specific exon HIPK3-T in the Homeodomain Interacting Protein Kinase 3 gene. By testing HIPK3-T exons of different intrinsic strengths, we found Tra2β most efficiently activated splicing inclusion of intrinsically...

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Detalles Bibliográficos
Autores principales: Grellscheid, Sushma Nagaraja, Dalgliesh, Caroline, Rozanska, Agata, Grellscheid, David, Bourgeois, Cyril F., Stévenin, James, Elliott, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185414/
https://www.ncbi.nlm.nih.gov/pubmed/21724598
http://dx.doi.org/10.1093/nar/gkr495

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