Flexible tethering of primase and DNA Pol α in the eukaryotic primosome

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The Pol α/primase complex or primosome is the primase/polymerase complex that initiates nucleic acid synthesis during eukaryotic replication. Within the primosome, the primase synthesizes short RNA primers that undergo limited extension by Pol α. The resulting RNA–DNA primers are utilized by Pol δ a...

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Detalles Bibliográficos
Autores principales: Núñez-Ramírez, Rafael, Klinge, Sebastian, Sauguet, Ludovic, Melero, Roberto, Recuero-Checa, María A., Kilkenny, Mairi, Perera, Rajika L., García-Alvarez, Begoña, Hall, Richard J., Nogales, Eva, Pellegrini, Luca, Llorca, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185431/
https://www.ncbi.nlm.nih.gov/pubmed/21715379
http://dx.doi.org/10.1093/nar/gkr534
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