HBV-Specific Adaptive Immunity

The successful control of HBV infection requires an efficient expansion of distinct elements of the adaptive immune system (B cells, helper and cytotoxic T cells) that, due to the hepatotropic nature of HBV, need to operate in the liver parenchyma. In this respect, we will discuss broad features of...

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Detalles Bibliográficos
Autores principales: Bertoletti, Antonio, Tan, Anthony T., Gehring, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185487/
https://www.ncbi.nlm.nih.gov/pubmed/21994540
http://dx.doi.org/10.3390/v1020091
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author Bertoletti, Antonio
Tan, Anthony T.
Gehring, Adam J.
author_facet Bertoletti, Antonio
Tan, Anthony T.
Gehring, Adam J.
author_sort Bertoletti, Antonio
collection PubMed
description The successful control of HBV infection requires an efficient expansion of distinct elements of the adaptive immune system (B cells, helper and cytotoxic T cells) that, due to the hepatotropic nature of HBV, need to operate in the liver parenchyma. In this respect, we will discuss broad features of HBV immunity in patients with resolved or chronic HBV infection and analyze how the liver environment can directly modulate HBV-immunity.
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spelling pubmed-31854872011-10-12 HBV-Specific Adaptive Immunity Bertoletti, Antonio Tan, Anthony T. Gehring, Adam J. Viruses Review The successful control of HBV infection requires an efficient expansion of distinct elements of the adaptive immune system (B cells, helper and cytotoxic T cells) that, due to the hepatotropic nature of HBV, need to operate in the liver parenchyma. In this respect, we will discuss broad features of HBV immunity in patients with resolved or chronic HBV infection and analyze how the liver environment can directly modulate HBV-immunity. Molecular Diversity Preservation International (MDPI) 2009-07-27 /pmc/articles/PMC3185487/ /pubmed/21994540 http://dx.doi.org/10.3390/v1020091 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Bertoletti, Antonio
Tan, Anthony T.
Gehring, Adam J.
HBV-Specific Adaptive Immunity
title HBV-Specific Adaptive Immunity
title_full HBV-Specific Adaptive Immunity
title_fullStr HBV-Specific Adaptive Immunity
title_full_unstemmed HBV-Specific Adaptive Immunity
title_short HBV-Specific Adaptive Immunity
title_sort hbv-specific adaptive immunity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185487/
https://www.ncbi.nlm.nih.gov/pubmed/21994540
http://dx.doi.org/10.3390/v1020091
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