Adaptive Immunity to Hepatitis C Virus

The precise role of adaptive immune responses in the clinical outcome of HCV infection is still only partially defined. Recent studies suggest that viral-host cell interactions during the acute phase of infection are essential for viral clearance or progression into chronic HCV infection. This revie...

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Detalles Bibliográficos
Autores principales: Zeisel, Mirjam B., Fafi-Kremer, Samira, Robinet, Eric, Habersetzer, François, Baumert, Thomas F., Stoll-Keller, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185498/
https://www.ncbi.nlm.nih.gov/pubmed/21994550
http://dx.doi.org/10.3390/v1020276
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author Zeisel, Mirjam B.
Fafi-Kremer, Samira
Robinet, Eric
Habersetzer, François
Baumert, Thomas F.
Stoll-Keller, Françoise
author_facet Zeisel, Mirjam B.
Fafi-Kremer, Samira
Robinet, Eric
Habersetzer, François
Baumert, Thomas F.
Stoll-Keller, Françoise
author_sort Zeisel, Mirjam B.
collection PubMed
description The precise role of adaptive immune responses in the clinical outcome of HCV infection is still only partially defined. Recent studies suggest that viral-host cell interactions during the acute phase of infection are essential for viral clearance or progression into chronic HCV infection. This review focuses on different aspects of the adaptive immune responses as determinants of the different outcomes of HCV infection, clearance or persistent infection, and outlines current concepts of HCV evasion strategies. Unravelling these important mechanisms of virus-host interaction will contribute to the development of novel strategies to prevent and control HCV infection.
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spelling pubmed-31854982011-10-12 Adaptive Immunity to Hepatitis C Virus Zeisel, Mirjam B. Fafi-Kremer, Samira Robinet, Eric Habersetzer, François Baumert, Thomas F. Stoll-Keller, Françoise Viruses Review The precise role of adaptive immune responses in the clinical outcome of HCV infection is still only partially defined. Recent studies suggest that viral-host cell interactions during the acute phase of infection are essential for viral clearance or progression into chronic HCV infection. This review focuses on different aspects of the adaptive immune responses as determinants of the different outcomes of HCV infection, clearance or persistent infection, and outlines current concepts of HCV evasion strategies. Unravelling these important mechanisms of virus-host interaction will contribute to the development of novel strategies to prevent and control HCV infection. Molecular Diversity Preservation International (MDPI) 2009-09-08 /pmc/articles/PMC3185498/ /pubmed/21994550 http://dx.doi.org/10.3390/v1020276 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Zeisel, Mirjam B.
Fafi-Kremer, Samira
Robinet, Eric
Habersetzer, François
Baumert, Thomas F.
Stoll-Keller, Françoise
Adaptive Immunity to Hepatitis C Virus
title Adaptive Immunity to Hepatitis C Virus
title_full Adaptive Immunity to Hepatitis C Virus
title_fullStr Adaptive Immunity to Hepatitis C Virus
title_full_unstemmed Adaptive Immunity to Hepatitis C Virus
title_short Adaptive Immunity to Hepatitis C Virus
title_sort adaptive immunity to hepatitis c virus
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185498/
https://www.ncbi.nlm.nih.gov/pubmed/21994550
http://dx.doi.org/10.3390/v1020276
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AT baumertthomasf adaptiveimmunitytohepatitiscvirus
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